One and One - One of the approximately 239,487 Irish pubs in Manhattan, One and One separates itself from the pack with great drink specials, weekend DJs, and a fancy-schmancy menu that even includes brunch. Located at First Avenue and 1st Street, it attracts a varied crowd, ranging from hipsters to Midtowners to everyone in between. Come after work for happy hour, where drink specials abound: $4 beers (domestic and imported) and $4 mixed drinks. The menu is surprisingly upscale (and reasonably priced), featuring grilled free-range chicken and even an Irish tapas selection. So throw a few pints back and let the luck of the Irish be with you.